Microsoft Copilot Studio has clear advantages for organizations deeply integrated with Microsoft 365, offering native access to Teams, SharePoint, Office apps, and enterprise governance features. Autonoly can work with Microsoft tools through APIs but won't have the same depth of integration or compliance features.

Autonoly is designed to work across any platform or tool ecosystem without dependencies on specific vendors. Copilot Studio requires Microsoft 365 licensing and works best within Microsoft's ecosystem. For diverse or non-Microsoft environments, Autonoly offers more flexibility.

Copilot Studio provides immediate value through pre-built agents and enterprise features for Microsoft customers. Autonoly's autonomous learning agents offer long-term value by continuously improving performance without manual updates. The choice depends on whether you prioritize immediate enterprise features or evolving automation intelligence.